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Fig. 6 | Genome Medicine

Fig. 6

From: PLCG2 is associated with the inflammatory response and is induced by amyloid plaques in Alzheimer’s disease

Fig. 6

Overview of our findings for PLCG2 in the brain and plaque-associated microglia. PLCG2 expression was increased in LOAD patients and was associated with plaque density. PLCG2 was increased exclusively in microglia in the AD mouse model. The inflammation-related pathways were identified in human and Plcg2-inactivated mouse brains and PLCG2 co-expression network analysis of human microglia single-cell RNA-Seq

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Genome Medicine

ISSN: 1756-994X

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