Table 1 Characteristics of the seven studies included in the meta-analysis
From: Meta-analysis identifies common gut microbiota associated with multiple sclerosis
First author | PMID | Country, state or city | DNA extraction kit | 16S rRNA gene region | Sequencing platform | Age (years, mean ± SD | Number of male to female | BMI (mean ± SD | Number of analyzed subjects | Sum | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Control | MS | Control | MS | Control | MS | Control | MS | |||||||
Chen | 27346372 | USA, Minnesota | MoBio | V3-V5 | Illumina | 40.3 ± 7.3 | 42.9 ± 10.6 | 14:22 | 10:21 | 27.8 ± 4.7 | 28 ± 6.3 | 36 | 31 | 67 |
Cekanaviciute | 28893978 | USA, California | MoBio | V4 | Illumina | 46.0 ± 13.7 | 40.9 ± 12.2 | 28:25 | 21:39 | NA | NA | 57 | 60 | 117 |
Cantoni | 35094961 | USA, Missouri | MoBio | V1-V3 | Illumina | 38.9 ± 7.3 | 41.8 ± 9.3 | 4:21 | 3:22 | 26.9 ± 6.3 | 27.1 ± 7.4 | 25 | 25 | 50 |
Ni Choileain | 32743517 | USA, Connecticut | MoBio | V4 | Illumina | 45.0 ± 12.0 | 42.0 ± 13.0 | 12:27 | 4:22 | 27.0 ± 5.0 | 29 \(.0\) ± 7.0 | 39 | 26 | 65 |
Jangi | 27352007 | USA, Massachusetts | MoBio | V4 | Illumina | 42.2 ± 9.6 | 49.7 ± 8.5 | 7:37 | 19:42 | 26.4 ± 6.3 | 27.2 ± 4.7 | 44 | 61 | 105 |
Miyake | 26367776 | Japan, Tokyo | In_house | V1-V2 | 454 | NA | 36.0 ±7.4 | NA | 6:14 | NA | NA | 32 | 20 | 52 |
Zeng | 31108132 | China, Guangdong | QIAamp | V3-V4 | Illumina | 29.0 ± 10.7 | 35.2 ± 9.0 | 13:21 | 13:21 | 21.7 ± 2.8 | 21.1 ± 2.9 | 34 | 34 | 68 |
Total number of subjects: | 267 | 257 | 524 | |||||||||||