Fig. 4

Stroke-induced changes in microglia are similar between male and female mice. A Split view of UMAP plot of four groups: female/sham (F_Sham), female/stroke (F_Stroke), male/sham (M_Sham), and male/stroke (M_Stroke). B Stacked bar plots illustrating the proportions of each microglia subset in the four experimental groups. C, D Volcano plots showing differentially expressed genes in microglia between stroke and sham groups. The gene selection criteria are Log2FC > 0.25 or < -0.25 and p_adj < 0.01. The two vertical dot lines represent fold changes of − 1.5 and 1.5