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Fig. 3 | Genome Medicine

Fig. 3

From: Ancestry-aligned polygenic scores combined with conventional risk factors improve prediction of cardiometabolic outcomes in African populations

Fig. 3

Association analysis of the PGS and non-genetic factors with seven CVD-associated outcomes. Logistic regression analyses assessing the association of each of the 14 derived PGS and 10 non-genetic factors with the seven selected CVD-disease outcomes. Significant associations with PGS are coloured in red, and significant associations with non-genetic factors are coloured in blue. Maximum case numbers are indicated by N = . CVD, cardiovascular disease; DLD, dyslipidaemia; HA, heart attack; HTN, hypertension; OBS, obesity; T2D, type 2 diabetes; DBP, diastolic blood pressure; SBP, systolic blood pressure; LDL, low-density lipoprotein; HDL, high-density lipoprotein; TC, total cholesterol; TG, triglycerides

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Genome Medicine

ISSN: 1756-994X

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