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Fig. 4 | Genome Medicine

Fig. 4

From: Integrated analyses of multi-omic data derived from paired primary lung cancer and brain metastasis reveal the metabolic vulnerability as a novel therapeutic target

Fig. 4

The landscape of somatic copy-number alteration in paired primary lung cancer and brain metastasis (BrM) specimens. a, b GISTIC amplification (a) and deletion (b) plots of primary lung cancer (n = 119) and BrM (n = 119) samples. In the top figure, red line is the amplification in BrM, and gray line is amplification in primary; in the both figures, blue line is the deletion in BrM, and gray line is deletion in primary. c–f. Four representative GISTIC plots showing regions of candidate driver genes of BrM compared to primary lung cancer

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Genome Medicine

ISSN: 1756-994X

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