Fig. 5

Reconstructed viralgenomes from children with clinically diagnosed acute sinusitis. A Bar graph depicting the number of reconstructed genomes for various species of respiratory viruses across the full dataset (N = 196 total viruses reconstructed from 163 samples). B Read pileups for three selected samples showing sequencing reads mapped to reference genomes of human coronavirus (HCoV) OC43 (NC_006213), RSV (NC_001781), and enterovirus D68 (NC_038308). C Phylogenetic analysis of three reconstructed viral genomes and their top 25 closest matching complete genomes from BLAST. Each newly reconstructed virus (red) is a unique strain that clusters as a distinct branch within its phylogenetic tree