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Fig. 7 | Genome Medicine

Fig. 7

From: DNA methylation memory of pancreatic acinar-ductal metaplasia transition state altering Kras-downstream PI3K and Rho GTPase signaling in the absence of Kras mutation

Fig. 7

Joint gene expression signatures at a single-cell resolution. A Example ADM cells co-expressing markers of acini (Pnliprp2, Gp2), ducts (Tff1, Krt19), panINs (Muc5ac), the PI3K pathway (Akt1, Pip5k1c, Pik3r2, Itpr3), and the AP1 complex (Jund). B Violin plots of normalized gene pair co-expression proportion in each cell for the two labeled categories. n = 19,776 cells. p-values: Wilcoxon rank sum test

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