Fig. 5
From: Rare damaging CCR2 variants are associated with lower lifetime cardiovascular risk
Phenome-wide association study of the damaging M249K CCR2 variant and associations with overall survival. A Results from a phenome-wide association study in UK Biobank and the Geisinger DiscovEHR-MyCode cohort for the M249K CCR2 variant among participants of European ancestry. Only phecodes with ≥ 10 cases in UK Biobank were analyzed. We present the names of phenotypes associated with rare CCR2 variants at p < 0.05. Only myocardial infarction reached an FDR-corrected p value of < 0.05. The results are presented as log-odds ratios (log-OR). B Kaplan–Meier curves for overall survival across 15 years of follow-up among carriers and non-carriers of the M249K CCR2 variant in the European subset of UK Biobank participants