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Fig. 5 | Genome Medicine

Fig. 5

From: Distinct pathway-based effects of blood pressure and body mass index on cardiovascular traits: comparison of novel Mendelian randomization approaches

Fig. 5

Matrix of empirically derived (1000 replicates) p values for distribution of effect size differences between pathway-partitioned (Mendelian) instruments and tissue-partitioned (coloc) instruments in 1-sample and 2-sample MR setting (univariable and multivariable) using body mass index (BMI) and blood pressure—systolic (SBP) and diastolic (DBP) as exposures and cardiometabolic traits as outcomes (AF, CHD, MI, HF, stroke, T2D, LDVEDV, LVEF, LVESV, SV). p values < 0.05 are highlighted in dark red

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Genome Medicine

ISSN: 1756-994X

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