Fig. 4
From: A multi-omic approach implicates novel protein dysregulation in post-traumatic stress disorder
miRNA dysregulation in PTSD and its effect on the proteome. A Comparison of miRNA abundance captured using bulk mRNA-seq and smRNA-seq results. B Volcano plots showing differential expression patterns of miRNAs in PTSD DLPFC and sgPFC regions. Dashed lines: log2(fold change) = ± 0.5 and P-value = 0.05. C Examples of correlations between miRNA MIR589 and disease-associated protein LY6H. D miRNA enrichment analysis of DEPs to identify regulatory miRNAs and their targets. Bar heights (signed − logP) indicate significances of enrichment