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Fig. 2 | Genome Medicine

Fig. 2

From: Insertion sequences accelerate genomic convergence of multidrug resistance and hypervirulence in Klebsiella pneumoniae via capsular phase variation

Fig. 2

IS-mediated high-frequency inactivation of the CPS locus in NK01067 strain. a Proportion of NM-T colonies resulting from the inactivation of three genes—wcaJ, wza, and wzc—mediated by IS5 and ISKox3 elements. Sequence alignment of the K-loci between the wild type and mutants: b wcaJ::IS5, c wza::ISKox3, d wzc::IS5. IS elements are depicted in red. Direct repeats flanking IS elements are shown: 4 bp for IS5 and 8 bp for ISKox3

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