Fig. 3

The acquisition of plasmid pNK01067-NDM- 1 in NK01144 results in an increased frequency of IS-mediated inactivation of the CPS locus. a The percentage of M–O and NM-T colonies present. b Sequence alignment of the K-loci between the wild type and mutants: among the 30 detected colonies, two were wzy::IS5 and 26 were wzy::ISKox3. IS elements are depicted in red. Direct repeats (DR) flanking IS elements are shown: 4 bp for IS5 and 8 bp for ISKox3